Mauve 1.2.3 review
DownloadMauve is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion.
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Mauve is a system for efficiently constructing multiple genome alignments in the presence of large-scale evolutionary events such as rearrangement and inversion.
Multiple genome alignment provides a basis for research into comparative genomics and the study of evolutionary dynamics on a new scale. Aligning whole genomes is a fundamentally different problem than aligning short sequences.
Mauve has been developed with the idea that a multiple genome aligner should require only modest computational resources. It employs algorithmic techniques that scale well in the amount of sequence being aligned.
For example, a pair of Y. pestis genomes can be aligned in under a minute, while a group of 9 divergent Enterobacterial genomes can be aligned in a few hours.
What's New:
New features:
Display each component of multi-part features (e.g. a multiple exon gene) as a linked series of boxes
Display repeat_region annotations from GenBank files
Improved load time for previously viewed alignments using a disk-based alignment cache
Added a help menu item that will clear the on-disk alignment cache
Colorized the similarity plots, grey was starting to depress our entire lab.
Support for highlighting arbitrary regions of the sequence by holding the shift key while clicking and dragging on the display
Faster nucleotide display when zoomed in closely
Bug fixes:
Fixed GUI interface for setting the minimum seed size (Thanks to Bill Bruno and Todd Treangen)
Fixed mouseover, highlighting, and display alignment in the LCB display mode (used when the Full Alignment option is disabled).
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